目的探讨经鼻持续气道正压通气(NCPAP)治疗新生儿呼吸衰竭疗效。方法78例呼吸衰竭新生儿,其中Ⅰ型呼衰30例,Ⅱ型呼衰48例,给予NCPAP治疗,观察患儿在NCPAP前,NCPAP后6 h、24 h的临床及血气变化,比较Pa02及PaC02的变化。结果78例患儿经NCPAP治疗后呼吸困难及缺氧征均有不同程度好转,血气Pa02明显提高(P<0.05),PaC02显著下降(P<0.01)。结论NCPAP可以改善氧合和通气,对Ⅰ型、Ⅱ型新生儿呼衰均有疗效。 Objective To investigate the efficacy of nasal continuous positive airway pressure (NCPAP) in neonatal respiratory failure. Methods A total of 78 neonates with respiratory failure were enrolled in this study. Among them, 30 were type Ⅰ respiratory failure and 48 were type Ⅱ respiratory failure. NCPAP treatment was used to observe the clinical and blood gas changes of children before and after NCPAP 6 h and 24 h. PaC02 changes. Results 78 cases of children with dyspnea and hypoxia after NCPAP treatment improved in varying degrees, blood gas Pa02 was significantly increased (P <0.05), PaCO2 decreased significantly (P <0.01). Conclusion NCPAP can improve oxygenation and ventilation, and is effective in treating type Ⅰ and type Ⅱ neonatal respiratory failure.