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目的观察口服葡萄糖酸锌治疗婴幼儿急性腹泻的疗效。方法将140例腹泻婴幼儿按随机数字表法分为治疗组和对照组各70例。2组均予综合治疗(胃肠黏膜保护剂、微生态调节剂、抗病毒等治疗),治疗组在综合治疗的基础上加用葡萄糖酸锌口服液口服。结果治疗组脱水纠正时间、退热时间、止泻时间及总病程较对照组明显缩短(P均<0.01),治疗组总有效率95.71%,对照组82.86%,2组比较差异有统计学意义(P<0.01)。结论婴幼儿急性腹泻在综合治疗的基础上加用葡萄糖酸锌可提高疗效,较快缓解病情,缩短病程。
Objective To observe the efficacy of oral zinc gluconate in the treatment of infant acute diarrhea. Methods 140 cases of diarrhea infants and young children were divided into treatment group and control group according to random number table method in 70 cases. The two groups were given comprehensive treatment (gastrointestinal mucosal protective agent, micro-ecological regulator, anti-virus treatment). The treatment group was treated with oral zinc gluconate orally on the basis of comprehensive treatment. Results The dehydration correction time, antipyretic time, antidiarrheal time and the total duration of disease in the treatment group were significantly shorter than those in the control group (P <0.01). The total effective rate was 95.71% in the treatment group and 82.86% in the control group. There was significant difference between the two groups (P <0.01). Conclusion Infantile acute diarrhea combined with zinc gluconate on the basis of comprehensive treatment can improve the curative effect, relieve the disease faster and shorten the course of the disease.