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目的分析云南省大姚县居民高血压、糖尿病、冠心病和脑卒中4种肥胖相关慢性病疾病负担,为采取相应的预防控制措施提供参考依据。方法采用分层随机抽样方法于2015年1月对在云南省大姚县抽取的2 479名≥35岁农村居民进行问卷调查和体格检查,采用伤残调整生命年(DALY)评价4种肥胖相关慢性病的疾病负担。结果云南省大姚县≥35岁农村居民肥胖和中心性肥胖患病率分别为6.9%和39.9%,高血压、糖尿病、冠心病和脑卒中4种相关慢性病患病率分别为40.4%、6.1%、5.5%和1.9%;高血压、糖尿病、冠心病和脑卒中每千人口DALY值分别为2.0、3.4、32.4和24.0;男性居民糖尿病、冠心病和脑卒中的每千人口DALY值分别为3.7、34.9和27.2,高于女性居民的3.0、30.2和21.0,高血压的每千人口DALY值为1.9,低于女性居民的2.1;多因素logistic回归分析结果显示,在调整了性别、年龄、文化程度、婚姻状况、家庭年人均收入、疾病家族史、吸烟等混杂因素后,肥胖居民患高血压、糖尿病、冠心病和脑卒中的风险为非肥胖居民的2.1、3.5、4.8和6.1倍,中心性肥胖居民患高血压、糖尿病、冠心病和脑卒中的风险为非肥胖居民的2.3、2.4、1.9和5.2倍(均P<0.05);4种肥胖相关慢性病的总DALY值为17 453.6,其中15.9%归因于肥胖,41.2%归因于中心性肥胖。结论减少肥胖和中心性肥胖的发生有助于降低高血压、糖尿病、冠心病和脑卒中4种肥胖相关慢性病的疾病负担。
Objective To analyze the burden of diseases related to obesity-related chronic diseases such as hypertension, diabetes mellitus, coronary heart disease and stroke among residents in Dayao County, Yunnan Province, so as to provide reference for taking corresponding preventive and control measures. Methods A stratified random sampling method was used to conduct questionnaires and physical examinations on 2 479 rural residents aged 35 years or older in Dayao County, Yunnan Province in January 2015. Four obesity-related factors were assessed using disability-adjusted life year (DALY) The burden of disease on chronic diseases. Results The prevalence rates of obesity and central obesity in rural residents ≥35 years old in Dayao County, Yunnan Province were 6.9% and 39.9% respectively. The prevalence rates of four related chronic diseases such as hypertension, diabetes, coronary heart disease and stroke were 40.4% and 6.1% %, 5.5% and 1.9% respectively; the DALY values of hypertension, diabetes, coronary heart disease and stroke were 2.0, 3.4, 32.4 and 24.0 respectively; the DALY values of male residents with diabetes, coronary heart disease and stroke were 3.7, 34.9, and 27.2, respectively, higher than 3.0, 30.2, and 21.0 for female residents. The DALY value per 1000 population of hypertension was 1.9, which was lower than that of female residents.2. Multivariate logistic regression analysis showed that after adjustment for gender, The prevalence of hypertension, diabetes, coronary heart disease and stroke among obese residents was 2.1, 3.5, 4.8 and 6.1 times higher than that of non-obese residents after they were confronted with the following conditions: education level, marital status, per capita family income, family history of illness, smoking, The risk of hypertension, diabetes, coronary heart disease, and stroke among people with central obesity was 2.3, 2.4, 1.9 and 5.2 times higher than those of non-obese people (all P <0.05). The total DALY of 4 obesity-related chronic diseases was 17 453.6, 15.9% of them are attributed to obesity, 41. 2% attributed to central obesity. Conclusions Reducing the incidence of obesity and central obesity helps to reduce the burden of disease in four obesity-related chronic diseases such as hypertension, diabetes, coronary heart disease and stroke.