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炔羟雄烯唑(Danazol,DNZ)系男性化作用减弱的雄性激素。于1963年人工合成(Manson)。1971年在美国初次应用于临床。最初用于治疗子宫内膜异位症,以后又用于乳腺囊肿、遗传性血管神经性水肿、青春早熟、男子女性型乳房、月经过多、α_1抗-胰蛋白酶缺乏症及系统性红斑狼疮等疾患的治疗。1983年Ahn和Gralnick启用该药治疗
Danazol (DNZ) is an androgen that is less masculine. Synthesized in 1963 (Manson). 1971 in the United States for the first time in clinical. Initially used for the treatment of endometriosis, and later for breast cysts, hereditary angioedema, precocious puberty, men’s breasts, menorrhagia, α_1 anti-trypsin deficiency and systemic lupus erythematosus Illness treatment. 1983 Ahn and Gralnick to enable the drug treatment