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目的:探讨血管内超声对变异型心绞痛患者冠状动脉病变特征。方法:变异型心绞痛患者10例,稳定型心绞痛患者13例。对每例患者行冠状动脉造影及血管内超声检查。对病变斑块的性质、形态、部位、血管管腔面积狭窄程度、血管重构指数等指标进行分析。结果:变异型心绞痛组与稳定型心绞痛组最小斑块厚度、斑块偏心指数、局部面积狭窄率、管腔面积狭窄率指标差异有统计学意义。IVUS检测血管重构指数、正性重构、负性重构在2组差异有统计学意义。结论:变异型心绞痛患者冠状动脉血管内目标斑块以偏心性纤维化斑块为主,血管管腔面积狭窄程度以轻中度狭窄为主,血管重构以正性重构为主。变异型心绞痛患者冠状动脉有粥样硬化斑块的形成,管腔有不同程度的狭窄。
Objective: To investigate the characteristics of coronary lesions in patients with variant angina undergoing intravascular ultrasound. Methods: 10 patients with variant angina pectoris and 13 patients with stable angina pectoris. Coronary angiography and intravascular ultrasound were performed on each patient. The characteristics of lesion plaque, shape, location, stenosis of vascular lumen area, vascular remodeling index and other indicators were analyzed. Results: The minimum plaque thickness, plaque eccentricity index, local area stenosis rate and luminal stenosis rate in variant angina pectoris group and stable angina pectoris group were significantly different. IVUS detection of vascular remodeling index, positive remodeling, negative remodeling in the two groups was statistically significant. CONCLUSIONS: In patients with variant angina pectoris, the target plaque in coronary artery is predominantly eccentric plaque, and the degree of stenosis is mainly in mild to moderate stenosis. Vascular remodeling is mainly based on positive remodeling. Patients with variant angina coronary atherosclerotic plaque formation, the lumen has varying degrees of stenosis.