腮腺功能动态检测预测鼻咽癌患者放射敏感性

来源 :肿瘤学杂志 | 被引量 : 0次 | 上传用户:jack_123456
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
[目的]探讨用腮腺功能动态检测来预测鼻咽癌患者放射敏感性的可行性。[方法]用腮腺ECT前瞻性研究42例鼻咽癌病人放疗前、放疗20Gy及60Gy时腮腺摄取功能、排泌功能,统计分析皮肤黏膜敏感组与不敏感组间、鼻咽肿瘤组织局控组与残留组间,左、右腮腺摄取功能减退率、排泌功能减退率等指标间的差异。[结果]在放射敏感组,左右腮腺排泌功能减退率在20Gy、60Gy时均较不敏感组更明显(P<0.05),而两组间摄取功能减退率无差异。左右腮腺排泌功能减退在60Gy时局控组较残留组更明显,但20Gy时两组间左右腮腺排泌功能减退率无差异。左右腮腺摄取功能减退率在放疗20Gy至60Gy时变化不明显。左右腮腺排泌功能减退极为明显,20Gy时左、右腮腺极度减退者分别为23例(54.76%)、19例(45.24%),60Gy时左、右腮腺极度减退者分别为33例(78.57%)、35例(83.33%)。[结论]腮腺ECT动态检测结果显示,射线主要损伤腮腺的排泌功能,在皮肤黏膜放射反应敏感组,20Gy、60Gy时左右腮腺排泌功能减退率明显增加。在局控组,60Gy时左右腮腺排泌功能减退较残留组更明显,有可能作为预测鼻咽癌放射敏感性的指标。 [Objective] To explore the feasibility of using parotid gland dynamic test to predict the radiosensitivity of nasopharyngeal carcinoma patients. [Methods] The parotid gland ECT prospective study of 42 patients with nasopharyngeal carcinoma before radiotherapy, radiotherapy 20Gy and parotid gland 60Gy uptake and excretion function, statistical analysis of skin and mucous membrane sensitive group and not sensitive group nasopharyngeal tumor control group And the residual group, left and right parotid glands function decline rate, excretion function decline rate and other indicators between the differences. [Results] In the radiosensitive group, the excretion rate of left and right parotid glands was significantly lower than that of the non-sensitive group at 20 Gy and 60 Gy (P <0.05), while there was no difference between the two groups. Left and right parotid excretion dysfunction in the control group 60Gy control group more obvious than the residual group, but 20Gy left parotid between the two groups no difference in excretion function. Left and right parotid uptake rate of decline in the 20Gy 60Gy radiotherapy did not change significantly. There were 23 cases (54.76%) and 19 cases (45.24%) with paroxysmal hypo parotid hyperplasia at 20Gy respectively, and 33 cases (78.57% ), 35 cases (83.33%). [Conclusion] The results of dynamic examination of parotid ECT showed that the excretion function of the parotid gland, which is mainly damaged by radiation, was significantly increased in the mucosal radiosensitive sensitive group at 20Gy and 60Gy. In the local control group, excretion of parotid glands at 60 Gy was more pronounced than that of the residual group, which may be used as an index to predict radiosensitivity of NPC.
其他文献
在新课程改革中,初中物理教学工作面临着较为严峻的挑战,新课程理念要求教师在教学中能够充分体现学生的主体地位,激发学习积极性,拓展教学空间,营造更加素质化的物理教学模
通过历史上出现的一些主要的学术流派和学说,简述了图书馆学的产生和发展的历史,区分了图书馆学史与图书馆史的不同。 Through the history of some of the major academic
在教学中进行素质教育和开发学生潜能是当今教学改革的方向,素质教育和学生潜能的发挥成为专家、学者、教育同仁研究的热点.在教学实践中,教师要做更深入的讨论、探讨.
投入达百亿元之巨的农村现代中小学远程教育工程,于2007年全面收官.远程教育建构的农村中小学教育的信息化平台,作为均衡优质教育资源的必要手段,有力地推动了农村素质教育全
中国漫画大师廖冰兄,原籍广西象州,1915年出生于广州,2006年在广州去世。原名廖东生,曾用“郑育吾”等笔名,又以其妹廖冰得“冰兄”笔名而成名。他4岁父亲去世,母亲疯愈后改
科学发展日新月异,新课程改革随之如火如荼.面对新课标三位一体的教学目标、广泛的教学内容,怎样提高化学教学质量达成中考目标,培养学生学习知识的能力、创新的意识,提高学
中国农业大学教授、著名动物营养学家、农业教育家,本刊顾问戎易先生,因病医治无效,于2011年12月9日在北京逝世,享年89岁。戎易先生是浙江慈溪人,1922年7月出生,1948年10月参
介绍与分析了高校电子阅览室馆员素质的必要性与提高其素质的方法。 Introduces and analyzes the necessity and quality of librarians in electronic reading room in co
类癌又称类癌瘤,为神经内分泌肿瘤,其生长较一般腺癌为慢,为低度恶性肿瘤,多起源于神经外胚层的嗜银细胞。我科收住1例以腹泻为首发症状的支气管类癌,此类患者临床少见,易误
Frrest Gump~1 dies and goesHeaven.He is met at thearly Gate by St.Petermself.The gates areclosed,however,and Forrestapproaches~2 thegatekeeper.St.Peter says,“