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目的:分析促红细胞生成素联合右旋糖酐铁治疗维持性血液透析患者慢性贫血的疗效及护理措施。方法:选取72例维持性血液透析慢性贫血患者,按随机数字表法分成研究组和对照组各36例。对照组采用促红细胞生成素治疗,研究组采用促红细胞生成素联合右旋糖酐铁治疗。对照组治疗期间行常规护理,研究组治疗期间行综合性护理措施。对比两组患者治疗前、后的贫血指标[血清铁蛋白(SF)、血红蛋白(Hb)、血细胞比容(HCT)、红细胞(RBC)]及生活质量。结果:两组治疗前SF,Hb,HCT,RBC及生活质量得分比较,差异无统计学意义(P>0.05);研究组治疗后Hb,HCT,RBC及生活质量得分均明显高于对照组,差异有统计学意义(P<0.05);而两组治疗后SF比较,差异无统计学意义(P>0.05)。结论:促红细胞生成素联合右旋糖酐铁配以综合护理措施可有效改善维持性血液透析慢性贫血患者的营养状况和生活质量。
Objective: To analyze the curative effect and nursing measures of erythropoietin combined with iron dextran in treatment of chronic hemodialysis patients with chronic hemodialysis. Methods: A total of 72 patients with chronic hemodialysis patients with chronic hemodialysis were divided into study group (36 cases) and control group (36 cases) according to random number table. The control group was treated with erythropoietin, and the study group was treated with erythropoietin combined with iron dextran. The control group routine nursing during treatment, the study group during the comprehensive nursing care measures. The anemia indicators (serum ferritin, hemoglobin, hematocrit, red blood cell (RBC)) and quality of life before and after treatment were compared between the two groups. Results: There was no significant difference in SF, Hb, HCT, RBC and quality of life before treatment between the two groups (P> 0.05). The scores of Hb, HCT, RBC and quality of life in the study group were significantly higher than those in the control group (P <0.05). There was no significant difference in SF between the two groups after treatment (P> 0.05). Conclusion: The combination of erythropoietin and iron dextran with comprehensive nursing measures can effectively improve the nutritional status and quality of life of patients with chronic hemodialysis patients with chronic hemodialysis.