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目的:观察复方一枝蒿冲剂联合中西药治疗病毒性心肌炎(VMC)的临床疗效。方法:将268例VMC患者随机分为治疗组(一枝蒿组和牛磺酸组)和对照组(西药组),并辅以其它中西药进行对比治疗观察。结果:一枝蒿组在临床症状、心电图、超声心动图、心肌损伤指标改善和柯萨奇病毒-IgM及肠病毒-RNA的转阴等方面都具有显著治疗效果,总有效率达85.1％,与牛磺酸组相比无显著性差异(P>0.05),与对照组相比差异显著(P<0.05或P<0.01)。结论:复方一枝蒿联合黄芪和辅酶Q10等中西药治疗VMC疗效显著,值得临床推广应用。
Objective: To observe the clinical curative effect of compound YiJiaowei granule combined with western medicine in the treatment of viral myocarditis (VMC). Methods: A total of 268 patients with VMC were randomly divided into treatment group (Artemisia annua L. group and taurine group) and control group (Western medicine group), supplemented by other Chinese and Western medicines for comparison and treatment. Results: The Artemisia annua group had significant curative effect in clinical symptoms, electrocardiogram, echocardiography, improvement of myocardial injury index and negative conversion of coxsackievirus-IgM and enterovirus-RNA with a total effective rate of 85.1% There was no significant difference between taurine group and control group (P <0.05 or P <0.01). Conclusion: The combination of Radix Astragali and Radix Astragali and Coenzyme Q10 in the treatment of VMC has significant curative effect and is worthy of clinical application.