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文献报道蓖麻(Ricinus communis)种子可作为口服避孕药使用。本实验旨在进一步研究蓖麻种子乙醚提取物18312-J的抗孕活 性。 实验对象为健康的成年Wistar大鼠和未成年雌性小鼠。①抗受孕作用实验:在动物发情期使动物交配,在动物交配前2日每日给予18312-J。②雌激素样作用实验:未成年雌性小鼠连续4天给药(1.2g/k8,皮下注射)后,将其处死,子宫称重。对摘除卵巢的小鼠进行同样处置。③黄体酮样作用实验:对成年
The literature reports that Ricinus communis seeds can be used as oral contraceptives. The purpose of this experiment was to further study the anti-pregnant activity of castor seed ether extract 18312-J. Subjects were healthy adult Wistar rats and underage female mice. 1 Anti-conception experiment: Animals were mated during animal estrus and given 18,312-J daily 2 days prior to mating. 2 Estrogen-like effect experiment: The immature female mice were administered for 4 consecutive days (1.2 g/k8, subcutaneous injection), sacrificed and the uterus was weighed. The same treatment was performed on the ovariectomized mice. 3 Progesterone-like Action Experiments: For Adulthood