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目的:探讨神经内镜联合荧光造影在前循环动脉瘤夹闭术中的应用价值。方法:以2018年10月至2019年1月武汉大学中南医院神经外科收治的15例前循环动脉瘤患者为研究对象,在动脉瘤夹闭术中使用神经内镜联合吲哚菁绿荧光造影,以了解动脉瘤形态, 观察瘤颈具体位置、与载瘤动脉关系,夹闭动脉瘤后载瘤动脉有无狭窄、夹闭不全以及动脉瘤后壁下隐藏的穿通支血管有无误夹。结果:15例动脉瘤夹闭全部成功(15/15),3例动脉瘤夹闭后使用吲哚菁绿血管造影(ICGA)及神经内镜观察后,发现动脉瘤颈残留,给予调整动脉瘤夹位置或补加动脉瘤夹,有1例脉络膜前动脉瘤夹闭后发现误夹脉络膜前动脉,给予调整动脉瘤夹后再次使用ICGA及神经内镜观察,脉络膜前动脉通畅,有1例A1段动脉瘤夹闭后,使用ICGA及神经内镜观察发现有穿支血管被误夹,给予调整动脉瘤夹后血管通畅,本组患者无手术相关致死、致残病例,也无植物生存状态病例。结论:在开颅动脉瘤夹闭术中,使用神经内镜观察穿支血管有无误夹及动脉瘤是否夹闭完全较不使用神经内镜和(或)吲哚菁绿荧光造影,可以减少术中脑血管痉挛,减少穿支血管误夹率,避免动脉瘤瘤颈残留,避免载瘤动脉狭窄或闭塞,减少术后并发症。“,”Objective:To explore the value of neuroendoscopy combined with fluorescence angiography in anterior circulation aneurysm clipping.Methods:A total of 15 patients with anterior circulation aneurysm from Department of Neurosurgery, Zhongnan Hospital of Wuhan University between October 2018 and January 2019 were enrolled. Neuroendoscopy combined with indocyanine green fluorescence angiography (ICGA) was used to determine the shape of the aneurysm, the specific location of the aneurysm neck and its relationship with the aneurysm-bearing artery during anterior circulation aneurysm clipping. Meanwhile, Neuroendoscopy combined with ICGA can be employed to observe whether there was stenosis and incomplete clamping of the aneurysm-bearing artery after clipping the aneurysm, and whether there was misclamping of the perforating branches hidden under the posterior wall of the aneurysm.Results:The success rate of aneurysm clipping in 15 cases was 15/15. After aneurysm clipping, ICGA and neuroendoscopy were performed. The residual aneurysm neck was detected in 3 cases, and the position of aneurysm clip was adjusted or aneurysm clips were added. In one case, the anterior choroidal aneurysm was found to be mistakenly clipped. After adjusting the aneurysm clip, ICGA and neuroendoscopy showed that the anterior choroidal artery was normal. In another case, the A1 segment aneurysm was clipped. ICGA and neuroendoscopy found that the perforating branch blood vessels were mistakenly clipped. After the adjustment of the aneurysm clip, the blood vessels recovered their patency. There were no surgical-related deaths, disability and coma cases in the study.Conclusions:During aneurysm clipping, neuroendoscopy combined with ICGA can reduce cerebral vasospasm, decrease the misclipping rate of perforation of blood vessels, and avoid residual neck of aneurysm, stenosis or occlusion of aneurysm-bearing artery by using neuroendoscopy to observe whether misclipping of the perforating branch vessels exist and whether the aneurysm is clipped. Therefore, it can reduce postoperative complications.