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突发性聋的病因和发病机制种类繁多,近年文献指出,患者有多种生化血凝及流变学紊乱。作者对50例患者进行了观察:女26,男24,年龄20～60岁,病期1天～2月,多数在发病14天内就诊。单耳46例,双耳4例。按发病原因分4组:(1)血管病变30例(高血压8,颈椎骨质增生12,神经循环张力障碍10);(2)病毒感染12例(损及同侧桥小脑角的颈后凹蛛网膜炎7,流感后耳蜗神经炎5);(3)颅脑外伤6例(颞岩骨折2,脑震荡4);(4)抗生素耳毒性作用2例。突发性聋患者血内葡萄糖、尿素、胆红素含量及肝功检查结果均正常,4例胆固醇含量增高可能与患者年龄有关(57～60岁)。血清激素含量正常,糖尿病患者血胰岛素、毒性甲状腺肿症患者血清甲状腺素及三碘甲状腺素含量变化均非突发性聋的主要原因。
Sudden deafness of the etiology and pathogenesis of a wide range of recent literature pointed out that patients with a variety of biochemical blood coagulation and rheological disorders. The authors of 50 patients were observed: female 26, male 24, aged 20 to 60 years, the period of 1 days to 2 months, most within 14 days of onset of treatment. 46 cases of single ear, ears in 4 cases. According to the cause of disease, there were 4 groups: (1) 30 cases of vascular disease (hypertension 8, cervical hyperostosis 12, nervous circulatory disturbance 10); (2) 12 cases of viral infection Arachnoiditis 7, post-influenza cochlear neuritis 5); (3) 6 cases of traumatic brain injury (rock fracture 2, concussion 4); (4) 2 cases of antibiotic ototoxicity. Patients with sudden deafness blood glucose, urea, bilirubin and liver function test results were normal, 4 cases of cholesterol levels may be related to patient age (57 to 60 years old). Serum hormone levels are normal, diabetic patients with blood insulin, toxic thyroid disease in patients with serum thyroxine and triiodothyronine levels are not the main cause of sudden deafness.