乳酸性酸中毒是代谢性酸中毒的一种,可发生于糖尿病患者,也可发生于非糖尿病患者,前者发生数约占乳酸性酸中毒总数的一半。虽然乳酸性酸中毒是糖尿病较少见的一种急性并发症,但由于不易及肘发现,且对其认识不足,故病死率极高。乳酸是体内一种强有机酸,可完全离子化。血乳酸升高不外乎乳酸生成增多和(或)乳酸利用减少。乳酸生成的主要来源是糖酵解,酵解过程中 Lactic acidosis is a metabolic acidosis, can occur in patients with diabetes, can also occur in non-diabetic patients, the former number of occurrence of lactic acidosis accounted for about half of the total number. Although lactic acidosis is an uncommon complication of diabetes mellitus, it is extremely ill because it is not easy to find and is not well known about it. Lactic acid is a strong organic acid in the body that can be completely ionized. Increased blood lactate is nothing more than an increase in lactate production and / or decreased lactate utilization. The main sources of lactate production are glycolysis and glycolysis