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目的:评价3种头孢菌素类抗生素治疗老年急性下呼吸道感染的成本‐效果。方法:运用药物经济学成本‐效果分析法,对头孢唑肟钠(A组)、头孢哌酮钠-舒巴坦钠(B组)、头孢他啶(C组)3种治疗方案进行回顾性分析。结果:3种治疗方案中,头孢哌酮钠-舒巴坦钠组疗效最好,成本最低。结论:3种头孢菌素类抗生素中,头孢哌酮钠-舒巴坦钠是治疗老年急性下呼吸道感染的最佳药物。
OBJECTIVE: To evaluate the cost-effectiveness of three cephalosporin antibiotics in the treatment of acute lower respiratory tract infections in the elderly. Methods: Cost-effectiveness analysis was used to analyze the three regimens of ceftizoxime (group A), cefoperazone sodium-sulbactam sodium (group B) and ceftazidime (group C). Results: Of the three treatment regimens, cefoperazone sodium-sulbactam sodium had the best efficacy and lowest cost. CONCLUSION: Cefoperazone sodium-sulbactam sodium is the best drug for the treatment of acute lower respiratory tract infection among the three cephalosporin antibiotics.