论文部分内容阅读
本文应用放射免疫方法测定了大白鼠不同情期中垂体的P物质含量变比及血清孕酮的含量,以探讨垂体P物质与卵巢孕酮生成之间的关系。实验结果表明,不同情期中,大白鼠垂体的P物质含量不同,以间情期为最高(3.97±2.12pmo/10mg湿重组织,X±SE)情前期次之(2.52±0.87),情期最低(1.96±0.81)。而血清孕酮含量呈相反变化,情期最高(74.62ng/ml±5.18,X±SE),情前期次之(50.12±5.38),间情期最低(24.33±8.11)。实验结果提示,垂体P物质可能通过抑制垂体的LH和FSH分泌而抑制卵巢孕酮生成。
In this paper, radioimmunoassay was used to determine the pituitary substance P content ratio and serum progesterone content during different estrous periods in rats to investigate the relationship between substance P and progesterone production in ovary. The experimental results showed that in different estrous periods, the content of substance P in the pituitary gland of rats was different, with the highest in inter-estrus (3.97 ± 2.12pmo / 10mg wet weight, X ± SE), followed by the antecedent (2.52 ± 0.87) Lowest (1.96 ± 0.81). Serum progesterone showed the opposite change, with the highest estrus (74.62ng / ml ± 5.18, X ± SE), the second estrus (50.12 ± 5.38) and the lowest estrus (24.33 ± 8.11). Experimental results suggest that pituitary substance P may inhibit ovarian progesterone production by inhibiting pituitary LH and FSH secretion.