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锌和其它营养素对免疫系统形成和稳定的重要性已得到公认。自Prasad于1961年首次发现人类的锌缺乏后,在美国低收入家庭的儿童、被收容所收养的人们、老年人和青少年孕妇中都发现有锌缺乏。许多疾病如镰状红细胞贫血、肾脏疾病、酒精中毒、胃肠道功能紊乱、烧伤及遗传性疾病如肠病性肢皮炎等均能导致锌缺乏。锌缺乏者血中淋巴细胞数减少,伤口愈合不良,对皮肤致敏无反应和反复发生感染,这些现象均提示锌缺乏时机体免疫功能受到损害。一、锌缺乏对宿主防御机制的影响
The importance of zinc and other nutrients in the formation and stabilization of the immune system has been recognized. Since Prasad first discovered human zinc deficiency in 1961, zinc deficiency has been found in low-income children in the United States, in pregnant women adopted by shelters, pregnant women in the elderly and adolescents. Many diseases such as sickle cell anemia, kidney disease, alcoholism, gastrointestinal disorders, burns and genetic diseases such as enteric dermatitis can cause zinc deficiency. Zinc deficiency in the blood to reduce the number of lymphocytes, wound healing, sensitization of the skin no response and repeated infections, these phenomena suggest that zinc deficiency in immune function compromised. First, zinc deficiency on the host defense mechanism