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目的评价2000-2007年浙江省云和县鼠疫监测结果。方法在原鼠疫流行地区设立固定和流动监测点,开展室内外鼠密度、鼠体蚤和地面游离蚤的监测;并对监测中捕获的活鼠采集脏器样品进行细菌分离培养,同时采鼠血进行鼠疫F1抗体的检测。结果室内、外平均鼠密度分别为3.50%、3.60%;平均染蚤率为8.55%、总蚤指数为0.130;室内、外主要鼠种分别是褐家鼠和黑线姬鼠;鼠体蚤主要为不等单蚤和缓慢细蚤,本地未检获印鼠客蚤。细菌分离培养3551只活鼠,未分离到鼠疫菌;间接血凝试验法检测鼠血清6511份,结果均为阴性;用放射免疫沉淀试验法和金标法检测鼠血清11份,检出1份放射免疫沉淀试验阳性鼠血清。结论通过8年的系统监测,虽未分离到鼠疫菌,但检出放免阳性鼠血清1份,提示云和县可能存在鼠疫的疫情隐患,要加强对鼠疫的监控工作,以防止鼠疫的发生。
Objective To evaluate the results of plague surveillance in Yunhe County, Zhejiang Province from 2000 to 2007. Methods The fixed and mobile monitoring points were established in the plague-endemic areas to monitor the indoor and outdoor mouse density, fleas and free fleas on the ground. The live samples collected from the monitoring were collected for bacterial isolation and culture, and the blood was collected Detection of plague F1 antibody. Results The average indoor and outdoor mouse densities were 3.50% and 3.60% respectively. The average flea flea rate was 8.55% and the total flea index was 0.130. The main indoor and outdoor rat species were Rattus norvegicus and Apodemus agrarius respectively. For not waiting for a single flea and slow flea, local seized rat flea. 3551 live mice were isolated and cultured without bacteria, 6511 were detected by indirect hemagglutination test, all of them were negative. The serum of 11 rats were detected by radioimmunoprecipitation assay and gold standard method. Radioimmunoprecipitation test positive rat serum. Conclusion Although 8 isolates of Yersinia pestis have not been isolated from the system during the past eight years, one copy of the positive rat serum was detected, suggesting that there may be a hidden danger of plague in Yunhe County. Therefore, it is necessary to strengthen the monitoring of plague to prevent the occurrence of plague.