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目的:通过ZJU指数筛查我院30 826例体检人群中非酒精性脂肪肝(nonalcoholic fatty liver disease,NAFLD)的患病率及人群分布特点。方法:对体检人群的人体测量学和生化指标进行分析,计算ZJU指数数值。将研究对象按年龄、性别分组,基于ZJU指数筛查各组体检人群中NAFLD的患病率,比较不同年龄段和性别间患病率的差异。结果:130 826例研究对象中,基于ZJU指数计算所得NAFLD的患病率为34.83%,其中男性患病率显著高于女性患病率(40.53%vs.29.26%,χ~2=431.440,P=0.000);2在男性人群中,NAFLD最低患病率为21.67%,分布于<30岁年龄段;最高患病率为49.90%,分布于50~59岁年龄段,总体患病率呈先上升后下降的趋势(P_(trend)=0.000);3在女性体检人群中,NAFLD最低患病率为8.86%,分布于<30岁年龄段,最高患病率为58.70%,分布于≥70岁年龄段,总体患病率随着年龄的增长而呈现上升趋势(P_(trend)=0.000)。结论:我院体检人群NAFLD的总体患病率为34.83%。其中,男性人群为40.53%,女性人群为29.26%,且患病趋势随着年龄的增长而升高。
OBJECTIVE: To screen the prevalence and population distribution of nonalcoholic fatty liver disease (NAFLD) in 30 826 medical check-ups in our hospital by ZJU index. Methods: The anthropometric and biochemical indexes of the medical examination population were analyzed to calculate the ZJU index value. The subjects were grouped by age and sex, and the prevalence of NAFLD in the medical examination population of each group was screened based on the ZJU index. The differences in prevalence among different age groups and gender were compared. Results: Among 130 826 subjects, the prevalence of NAFLD based on the ZJU index was 34.83%, of which the prevalence of men was significantly higher than that of women (40.53% vs.29.26%, χ ~ 2 = 431.440, P = 0.000) .2 In the male population, the lowest prevalence of NAFLD was 21.67%, distributed in <30 years old; the highest prevalence was 49.90%, distributed in the age group of 50-59 years, the overall prevalence was first (P_ (trend_ = trend) = 0.000) .3 The lowest prevalence of NAFLD in female was 8.86%, which was distributed in <30 years old, the highest prevalence was 58.70% The age group, the overall prevalence increased with age and showed an upward trend (P_ (trend) = 0.000). Conclusion: The overall prevalence of NAFLD in our hospital was 34.83%. Among them, the male population was 40.53%, the female population was 29.26%, and the prevalence trend increased with age.