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目的探讨低分子肝素钠治疗急性期非大面积心源性脑栓塞患者的临床效果。方法选取2015年1月至2016年1月于沈阳市第五人民医院就诊的98例急性期非大面积心源性脑栓塞患者作为研究对象,按随机数字表法将其分为两组,49例行低分子肝素钠治疗,作为观察组,49例行阿司匹林治疗,作为对照组,比较两组患者治疗效果。结果治疗后,观察组患者NIHSS评分明显低于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者MBI评分明显高于对照组,差异有统计学意义(P<0.05);观察组治疗3个月后m RS评分为0级与1级患者所占比例均明显高于对照组,差异均有统计学意义(均P<0.05);观察组患者再梗死率明显低于对照组,差异有统计学意义(χ~2=5.269,P=0.022)。结论针对非大面积心源性脑栓塞患者行低分子肝素钠治疗效果显著,有利于促进患者神经功能恢复,并且能改善其生活能力。
Objective To investigate the clinical effect of low molecular weight heparin sodium in the treatment of acute non-large-area cardioembolism. Methods A total of 98 patients with acute noncardio-cerebral infarction who were admitted to the Fifth People’s Hospital of Shenyang City from January 2015 to January 2016 were selected as subjects and divided into two groups according to the random number table method. Routine low molecular weight heparin treatment, as the observation group, 49 cases of aspirin treatment, as a control group, the treatment effect of two groups were compared. Results After treatment, the NIHSS score in observation group was significantly lower than that in control group (P <0.05). After treatment, MBI score in observation group was significantly higher than that in control group (P <0.05) ; The observation group 3 months after the m RS score was 0 and 1 patients were significantly higher proportion of patients were significantly higher than the control group, the difference was statistically significant (P <0.05); the reinfarction rate was significantly lower in the observation group Control group, the difference was statistically significant (χ ~ 2 = 5.269, P = 0.022). Conclusion The treatment of low molecular weight heparin sodium in patients with non-large area heart-derived cerebral embolism is effective and can promote the recovery of neurological function and improve the living ability of patients.