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目的 本设计是在全肺CT 扫描基础上,选择具有代表上、中、下肺野3 个层面的CT 扫描,用于对应全肺层面的CT扫描在定量检测肺气肿上的贴切性研究。方法 选择- 960HU 作为区别正常肺密度区与肺低减损区的临界值,利用已有的计算机程序对55 例(慢性阻塞性肺疾患38 例,健康对照组17 例)临床资料进行分析,确定肺低减损区占肺层扫描面积总和的百分比,并与3 个层面的肺减损区百分比做比较。结果 3 个肺层面与全肺层面肺低减损区百分比(LAA%) 的相关系数为0.991,在肺扫描结果与肺功能相关性研究方面,3 个层面的肺低减损区百分比,3LAA% 与肺功能FEV1 % ,FEV1/FVC% ,DL/VA 显示出很好的相关性,相关系数分别是-0 .827、- 0 .793 、- 0.756 ,与全肺层面时的相关系性无差别(r= - 0 .819,- 0.789 ,-0 .753; P<0 .001)。结论 用3 个层面肺扫描在定量检测肺气肿改变方面基本上可达到全肺扫描同样的结果。
The purpose of this design is based on the CT scan of the whole lung, choose to have on behalf of the middle and lower lung field three levels of CT scan, corresponding to the whole lung level CT scan quantitative detection of emphysema in the relevance of the study. Method selection - 960HU as a cut-off value between normal lung density zone and low lung injury zone, using the existing computer program to analyze the clinical data of 55 cases (38 cases of chronic obstructive pulmonary disease, 17 cases of healthy control group) to determine the lung The percentage of low impairment zones to the sum of lung scan areas was compared with the percentage of lung impairment zones at three levels. Results The correlation coefficient of LAA% between the three lungs and the whole lung was 0.991. The correlation between lung scan results and pulmonary function was significant And lung function FEV1%, FEV1 / FVC%, DL / VA showed a good correlation, the correlation coefficient is -0. 827, - 0. 793, and - 0.756, respectively. There was no significant difference between the two groups (r = - 0.889, - 0.789, -0.753; P <0.001). Conclusions The same results can be achieved with full lung scans with quantitative quantitative detection of emphysema using three-dimensional lung scans.