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目的观察碘伏联合克霉唑栓治疗妊娠期外阴阴道假丝酵母菌病的临床疗效。方法将100例外阴阴道假丝酵母菌病患者随机分为治疗组和对照组各50例。治疗组予0.5%碘伏原液擦洗阴道+克霉唑栓500mg塞阴道,隔3d后再用药1次。对照组予3%～4%碳酸氢钠液擦洗阴道+克霉唑栓500mg塞阴道,隔3d后再用药1次。观察2组临床疗效复发情况。结果治疗组治愈率明显高于对照组,复发率低于对照组,差异均有统计学意义(P<0.05)。结论碘伏联合克霉唑栓治疗妊娠期外阴阴道假丝酵母菌病效果好,安全性好,值得临床推广应用。
Objective To observe the clinical efficacy of iodophor and clotrimazole suppository in the treatment of vulvovaginal candidiasis during pregnancy. Methods 100 cases of vulvovaginal candidiasis were randomly divided into treatment group and control group of 50 cases. The treatment group to 0.5% iodophor stock solution scrub vagina + clotrimazole suppository 500mg plug the vagina, and then medication once every 3 days. The control group to 3% to 4% sodium bicarbonate solution scrub vagina + clotrimazole suppository 500mg plug the vagina, and then medication once every 3 days. The clinical efficacy of two groups observed the recurrence. Results The cure rate of the treatment group was significantly higher than that of the control group, the recurrence rate was lower than the control group, the difference was statistically significant (P <0.05). Conclusion Iodovir combined with clotrimazole suppositories for the treatment of vulvovaginal candidiasis during pregnancy is effective, safe and worthy of clinical application.