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目的探讨宫颈癌根治术中加行腹主动脉旁淋巴结切除在ⅠB2及ⅡA2期宫颈癌治疗中的临床应用价值。方法 80例ⅠB2及ⅡA2期宫颈癌患者,按照随机分配原则分为治疗组和对照组,每组40例。对于对照组患者采用宫颈癌根治术进行治疗,而对于治疗组患者除了使用宫颈癌根治术治疗还联合使用腹主动脉旁淋巴结切除术进行治疗。对比两组患者临床效果。结果治疗组手术时间(236.8±34.2)min和对照组手术时间(245.6±12.9)min相比差异无统计学意义(P>0.05),手术中出血量以及手术并发症发生率治疗组同对照组相比差异无统计学意义(P>0.05),但是治疗组患者中复发的人数显著的优于对照组,差异有统计学意义(P<0.05)。结论对于ⅠB2及ⅡA2期宫颈癌患者采用宫颈癌根治术中加行腹主动脉旁淋巴结切除进行治疗,能够使患者的复发率显著降低,提高患者的生存率,临床效果显著,值得广泛推广应用。
Objective To investigate the clinical value of adjuvant abdominal para-aortic lymph node dissection in the treatment of cervical cancer with stage ⅠB2 and Ⅱ A2 cervical cancer. Methods 80 cases of ⅠB2 and Ⅱ A2 cervical cancer patients were divided into treatment group and control group randomly according to the principle of random distribution, 40 cases in each group. Cervical cancer was treated with radical mastectomy in the control group, while patients in the treatment group were treated with radical resection of the para-aortic lymph node with the exception of cervical cancer radical mastectomy. The clinical effects of two groups were compared. Results There was no significant difference in operative time between the treatment group (236.8 ± 34.2) min and the control group (245.6 ± 12.9) min (P> 0.05), the amount of bleeding during operation and the incidence of surgical complications were the same as the control group (P> 0.05). However, the number of relapse patients in the treatment group was significantly better than that in the control group, with significant difference (P <0.05). Conclusions The treatment of patients with stage ⅠB2 and ⅡA2 cervical cancer by radical resection of para-aortic lymph node in cervical cancer patients can significantly reduce the recurrence rate and improve the survival rate of patients. The clinical effect is worthy of widespread application.