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目的:探讨肺癌肉瘤的发病、诊断、治疗及预后。方法:收集我院胸外科自 1964年 4月至 2000年 2月治疗的肺癌肉瘤 14例进行回顾性分析。结果:本组病例占同期肺部肿瘤的 0.26%,临床症状、影像学表现与肺癌相似。本组全部行根治性切除加区域淋巴结清扫,术后 4例辅以化疗, 2例辅以局部放疗, 2例辅以 LAK细胞免疫治疗。 3年生存率为 28.57%,中位生存时间为 31.9个月。结论:痰涂片细胞学检查和支气管纤维镜检查对术前获得病理确诊帮助不大,一般需术后全标本大切片病理证实。本病治疗一般首选手术治疗,但预后较差,生存期的长短似乎与病期关系不大,要提高疗效,需要在综合治疗方面做更多研究。
Objective: To investigate the pathogenesis, diagnosis, treatment and prognosis of lung cancer sarcoma. METHODS: We retrospectively analyzed 14 cases of lung cancer sarcoma treated in our hospital from April 1964 to February 2000. Results: The patients in this group accounted for 0.26% of lung tumors in the same period. The clinical symptoms and imaging findings were similar to those of lung cancer. All the patients underwent radical resection and regional lymph node dissection. Four patients received chemotherapy after the operation, two patients received local radiotherapy, and two patients received LAK cell immunotherapy. The 3-year survival rate was 28.57%, and the median survival time was 31.9 months. Conclusion: Sputum smear cytology and bronchial fiberoptic examination have little help in preoperative diagnosis of pathological diagnosis. It is generally necessary to verify the pathology of the entire specimen after large section biopsy. The surgical treatment of this disease is generally preferred, but the prognosis is poor, and the length of survival seems to have little to do with the disease period. To improve the therapeutic effect, more research needs to be done in comprehensive treatment.