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利用扫描电镜、X衍射仪以及红外漫反射仪,并通过对生物活性玻璃/聚乳酸组织工程支架在模拟体液(SBF)中失重率及模拟体液pH值的变化的检测,系统研究了生物活性玻璃/聚乳酸组织工程支架在SBF中的降解和矿化性能。结果发现:随着含有生物活性玻璃的聚乳酸支架在SBF溶液中浸泡时间的增长,SBF的pH值不断下降;含有生物活性玻璃的聚乳酸支架的质量不断下降。XRD、FTIR谱图和SEM图像表明:在SBF中浸泡一定时间后,有无定型的或结晶不完善的磷灰石在含有生物活性玻璃的聚乳酸支架的表面沉积形成。
Scanning electron microscopy, X-ray diffractometry and infrared diffuse reflectance spectroscopy were used to investigate the biodegradability of bioactive glass / PLA tissue engineering scaffolds in simulated body fluid (SBF) and the changes of simulated body fluid pH. Degradation and mineralization of polylactic acid tissue engineering scaffold in SBF. The results showed that the pH value of SBF decreased with the increase of soaking time of SBR solution containing biologically active glass, and the mass of PLA-containing PLGA decreased continuously. XRD, FTIR spectra and SEM images showed that amorphous or incompletely crystalline apatite was deposited on the surface of bioactive glass polylactic acid scaffold after soaking in SBF for a certain time.