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目的:探讨育龄妇女沙眼衣原体感染与不良孕产结局的关系。方法:采用荧光定量聚合酶链反应(FQ-PCR)技术对1969例育龄妇女宫颈分泌物标本进行沙眼衣原体(CT)检测。结果:总阳性率10.51%。继发不孕者阳性率为16.78%,显著高于普通孕妇的9.45%(P<0.01)。CT阳性孕妇异常妊娠结局率为27.63%,显著高于阴性孕妇的10.15%(P<0.01)。结论:育龄妇女CT感染是造成继发不孕、不良妊娠结局包括流产、早产等的重要因素之一。
Objective: To investigate the relationship between infection of Chlamydia trachomatis and the outcome of adverse pregnancy in women of childbearing age. Methods: The cervical secretions from 1969 women of childbearing age were tested for C. trachomatis (CT) by fluorescence quantitative polymerase chain reaction (FQ-PCR). Results: The total positive rate of 10.51%. The positive rate of secondary infertility was 16.78%, significantly higher than 9.45% of normal pregnant women (P <0.01). The abnormal pregnancy outcome rate of CT positive pregnant women was 27.63%, which was significantly higher than that of negative pregnant women (10.15%, P <0.01). Conclusion: CT infection in women of childbearing age is one of the important factors that cause secondary infertility and adverse pregnancy outcomes, including abortion and premature delivery.