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作者对3组病人进行了血清γ谷氨酰转肽酶(γGT)定量测定,观察其在支气管肺癌中早期发现肝转移的价值,同时与临床检查、肝功能试验和肝扫描作对照。第1组70例,为原发性支气管肺癌(多数属晚期),有肝转移者7例(10%),γGT均阳性,无1例假阴性,但有6%的假阳性,符合率94%。第2组45例,为转移性肺胸膜癌,其中6例有肝转移,5例γGT阳性,假阴性17%,假阳性5%,符合率78%。第3组38例酗酒者,非癌肿性呼吸道疾病而入院,13例(34%)γGT阳性,常与单纯性酒精中毒有关,戒酒后可使γGT恢复正常。
The authors performed quantitative measurement of serum gamma glutamyl transpeptidase (γGT) in three groups of patients to observe their value of early detection of liver metastases in bronchial lung cancer, and compared with clinical examination, liver function tests and liver scans. In the first group, 70 cases were primary bronchogenic carcinoma (mostly advanced stage), liver metastasis was found in 7 cases (10%), gamma GT was positive, no 1 case was false negative, but 6% were false positive, and the coincidence rate was 94%. . In the second group, 45 cases were metastatic pulmonary pleural carcinomas, of which 6 cases had hepatic metastases, 5 cases were gamma GT positive, false negatives were 17%, false positives were 5%, and the coincidence rate was 78%. The third group of 38 alcoholics admitted to the hospital with non-cancerous respiratory disease, 13 cases (34%) of gamma GT-positive, often associated with simple alcoholism, gamma GT returned to normal after drinking.