胰岛素抵抗 (insulin resistance)是机体对一定浓度的胰岛素的生物反应性低于正常 ,即对胰岛素不敏感。现已发现 ,高血压患者早期就存在胰岛素抵抗 ,在临界期高血压时 ,空腹血浆胰岛素水平已经高于健康人。因此 ,抗高血压药物对胰岛素抵抗的影响被认为是评价其优劣的一个重要指 Insulin resistance is the body’s biological response to a certain concentration of insulin is lower than normal, that is, insulin-insensitive. It has now been found that insulin resistance exists early in patients with hypertension and that fasting plasma insulin levels are already higher in healthy individuals than controls. Therefore, the impact of antihypertensive drugs on insulin resistance is considered to be an important indicator of its merits