精液分析是传统检测男性不孕的重要方法。不孕男性精子计数<20×10~6/ml占16%,在可生育的男性中,精子计数<20×10~6/ml占5%,但从未见有关精子数<5×10~6/ml还可生育的报道。本例男性患者26岁,婚后三年未孕。女方无异常。患者发育良好,无接触毒物、酒精及药物等历史,无家族不育史。精子计数<100,000/ml,睾丸活检示不完全成熟停滞,但曲细精管周边排列着大量精原细胞和初级精母细胞,少量次级精母细胞,精子细胞罕见。管腔内无精子。体检示患者生殖器正常,双侧睾丸25cm大小,硬度正常,未扪及精索静脉曲张。其黄体生成素、促卵泡素和睾丸酮水平正常。妻子的月经史,基础 Semen analysis is an important method of traditional detection of male infertility. Infertile men sperm count <20 × 10 ~ 6 / ml accounted for 16%, in fertile men, sperm count <20 × 10 ~ 6 / ml accounted for 5%, but never seen the number of sperm <5 × 10 ~ 6 / ml is also fertile reports. Male patients in this case 26 years of age, three years after marriage is not pregnant. No abnormality in the woman. Patients with well-developed, non-contact poisoning, alcohol and drug history, history of family history of infertility. Sperm count <100,000 / ml, testis biopsy showed incomplete maturation stagnation, but the seminiferous tubules arranged around a large number of spermatogonia and primary spermatocytes, a small amount of secondary spermatocytes, sperm cells rare. No sperm in the lumen. Physical examination showed normal genitals in patients, bilateral testis 25cm size, hardness is normal, no palpable varicocele. The luteinizing hormone, follicle stimulating hormone and testosterone levels. His wife’s history of menstruation, the foundation