Purpose: To evaluate (with three different electrophysiological methods) the r esidual retinal function in a selected group of patients with retinitis pigmento sa and remaining small central visual fields. Methods: Fourteen patients from se veral different genetic subgroups, who had been followed with visual acuity and visual field testing for periods up to 32 years, were examined. Ophthalmological examination included full-field electroretinography (ERG), multifocal electror etinography (mfERG) and multifocal visual evoked potential (mfVEP). Results: The ERGs were severely reduced in all patients. The mfERGs demonstrated the residua l central retinal function in five of the patients. The mfVEPs showed measurable amplitudes centrally in most of the patients. The follow-up examinations demon strated the slowly progressive course of the disease with preservation or only s light further loss of visual fields over a period of 7-32 years. Conclusion: Pa tients with retinitis pigmentosa may not always follow the typical natural cours e with progressive loss of visual fields, which may in some patients remain unaf fected over several decades. Multifocal ERG and mfVEP may be clinically useful f or evaluating remaining visual function in these patients. Methods: To evaluate (with three different electrophysiological methods) the r esidual retinal function in a selected group of patients with retinitis pigmento sa and remaining small central visual fields. Methods: Fourteen patients from se veral different genetic subgroups, who had been followed with visual acuity and visual field testing for periods up to 32 years, were examined. Ophthalmological examination included full-field electroretinography (ERG), multifocal electror etinography (mfERG) and multifocal visual evoked potential (mfVEP). Results: The ERGs were severely reduced in all The mfVEPs showed measurable amplitudes centrally in most of the patients. The follow-up examinations demon strated the slowly progressive course of the disease with preservation or only s light further. loss of visual fields over a period of 7-32 years. Conclusion: Pa tients with retinitis pigmentosa may not always follow the typical natural cours e with progressive loss of visual fields, which may in some patients remain unaf fected over several decades. Multifocal ERG and mfVEP may be clinically useful f or evaluating remaining visual function in these patients.