Two new diterpenoid lactones isolated from Andrographis paniculata

来源 :中国天然药物 | 被引量 : 0次 | 上传用户:hmtllgh
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
In the present study,two new diterpenoid lactones,3-deoxy-andrographoside (1) and 14-deoxy-15-methoxy-andrographolide (2),were isolated from the aerial parts of Andrographis paniculata.Their structures were elucidated by combination of NMR,MS,and chemical methods.The configurations of 1 and 2 were established based on the analysis of ROESY data and single crystal X-ray diffraction experiment.
其他文献
Benign prostatic hyperplasia (BPH) is an age-related disease of unknown etiology,characterized by prostatic enlargement coincident with distinct alterations in tissue histology.In the present study,we investigated whether triptolide can prevent testostero
There is an increasing interest in phytoestrogens due to their potential medical usage in hormone replacement therapy (HRT).The present study was designed to investigate the in vitro effects of estrogen-like activities of two widespread coumarins,osthole
Microglial activation and resultant neuroinflammatory response are implicated in various brain diseases including Alzheimer\'s disease and Parkinson\'s disease.Treatment with anti-neuroinflammatory agents could provide therapeutic benefits for such di