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目的观察双联抗血小板治疗短暂性脑缺血发作(TIA)的临床治疗效果。方法将我院2011年9月到2012年8月之间收录的76例短暂性脑缺血发作患者随机的分为两组,对照组38例患者给予阿司匹林治疗,而观察组的38例患者给予阿司匹林联合硫酸氢氯吡格雷进行治疗,观察两组的治疗效果。结果通过两组的治疗效果比较,1个月后两组患者治疗效果比较无明显的差异,(P>0.05);在3个月后两组的治疗效果比较具有明显的差异,观察组疗效明显的高于对照组情况,(P<0.05),统计学有意义。观察组的不良反应发生率明显的低于对照组的情况,比较具有明显的差异(P<0.05),统计学有意义。结论临床上对于短暂性脑缺血发作患者采取双联抗血小板聚集治疗具有较好的临床疗效,有效的改善患者的临床症状,不良反应少,值得临床中应用。
Objective To observe the clinical effect of double antiplatelet therapy on transient ischemic attack (TIA). Methods Totally 76 patients with transient ischemic attack included in our hospital from September 2011 to August 2012 were randomly divided into two groups. 38 patients in the control group were given aspirin, and 38 patients in the observation group were given Aspirin combined with clopidogrel hydrogen sulfate treatment, the two groups observed the effect of treatment. Results After two months of treatment, there was no significant difference in the treatment effect between the two groups after 1 month (P> 0.05). After 3 months, there was a significant difference in the treatment effect between the two groups, and the effect of the observation group was obvious Higher than the control group (P <0.05), statistically significant. The incidence of adverse reactions in the observation group was significantly lower than that in the control group, with significant difference (P <0.05), statistically significant. Conclusions The clinical application of double antiplatelet aggregation therapy in patients with transient ischemic attack has better clinical efficacy, effectively improving the clinical symptoms and adverse reactions, and is worthy of clinical application.