多发性骨髓瘤(multiple myeloma,MM)是浆细胞克隆性增生的恶性肿瘤。由于其起病缓慢,临床表现多样,诊断则完全依赖于实验室检查,因而易引起误诊。国内文献有关本病误诊的报道很多。实际上,对伴有高球蛋白血症的患者诊断并不困难,而对球蛋白不升高或仅轻度升高的患者,则容易引起 Multiple myeloma (MM) is a malignant tumor of clonal proliferation of plasma cells. Due to its slow onset, diverse clinical manifestations, the diagnosis is completely dependent on laboratory tests, which can easily lead to misdiagnosis. Domestic literature on the misdiagnosis of the disease a lot of reports. In fact, it is not difficult to diagnose patients with hypergammaglobulinemia, but to patients who do not have elevated or only mildly elevated globulin