PAM治疗有机磷——对硫磷农药中毒是有效的,可是治疗低毒性有机磷中毒经临床证实效果不佳,其理由何在,在使用上是否有问题,本文进行了解释。对硫磷和杀螟松农药的区别及PAM的作用:对硫磷和杀螟松结构式的不同,在于杀螟松多一个甲基,ChE的阻碍作用是在磷酯的分解部位,其结合点两者相同。PAM有使磷分离作用,在杀螟松中毒时也有效。杀螟松治疗时无效的原因,一般认为PAM与磷反应是1:1。对硫磷因毒性高,只有少量服用患者接受了治疗;而杀螟松毒性低,大量服用的患者也有机会 PAM treatment of organophosphate - parathion pesticide poisoning is effective, but the treatment of low toxicity organophosphate poisoning clinically proved ineffective, the reason why, in the use of any problems, this article is explained. The difference between parathion and fenitrothion pesticides and the role of PAM: parathion and fenitrothion structural formula is different from the fenitrothion one more methyl, ChE hindered the role of phosphorus ester in the decomposition of the site, the point of its combination Both are the same. PAM has the role of phosphorus separation, also effective in fenitrothion poisoning. Fenitidine treatment ineffective reasons, generally think PAM and phosphorus reaction is 1: 1. Parathion due to high toxicity, only a small number of patients taking the treatment; and fenitrothion low toxicity, taking a large number of patients have the opportunity