三苯氧胺是一种极低效的雌激素,对雌激素受体起竞争作用而产生抗雌激素作用,—般用干雌激素有关肿瘤的辅助治疗.本文报道用三苯氧胺对5例患有高泌乳素血症或溢乳症患者的疗效观察.1 材料与方法1.1 病员来源于1990年1月～1990年9月间我院妇科专科门诊,患者均为双侧乳房有溢乳或相隔1周的2次血清泌乳素值≥700(?)/ml,且基础体温单相的不孕患者,其年龄29～38岁,平均不孕年限为4年.1.2 方法:于三苯氧胺治疗前先观察每个患者1～2个月经周期,井测定血清PRL、FSH、LH、E_2与T_3、T_4等.于月经来潮第5天开始服用三苯氧胺10mg/次, Tamoxifen is a very inefficient estrogen that competes with estrogen receptors to produce anti-estrogen effects, and as an adjuvant treatment of estrogen-related tumors.This article reports the use of tamoxifen in 5 patients with high prolactin Hemolytic disease or galactorrhea observed in the efficacy of 1.1 Materials and Methods 1.1 The patient from January 1990 to September 1990 in our hospital gynecological specialist outpatient, patients were bilateral breast galactorrhea or 2 weeks apart serum Prolactin value ≥ 700 (?) / Ml, and the basic body temperature of infertility single-phase patients, aged 29 to 38 years, the average age of 4 years of infertility.1.2 Methods: Before the tamoxifen treatment observed in each patient 1 ~ 2 menstrual cycle, and measured serum PRL, FSH, LH, E_2 and T_3, T_4, etc. In the menstrual cramps on the 5th day to take tamoxifen 10mg / time,