临床资料曾报道,在停用避孕药后常伴发闭经。已知,黄体生成素释放激素(LH-RH)可能与垂体中黄体生成素(LH)和卵泡刺激素(FSH)的合成以及释放有关。外源注射的 LH-RH 与垂体释放的 LH 和 FSH 之间存在剂量关系。本文观察并比较了两组继发性闭经患者的 LH 和 FSH 的基础水平,以及对外源注射的 LH-RH 的反应,试图阐明无排卵的病因。 Clinical data have been reported in patients with contraceptives often accompanied by amenorrhea. It is known that luteinizing hormone-releasing hormone (LH-RH) may be involved in the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the pituitary. There is a dose-related relationship between exogenously injected LH-RH and pituitary-released LH and FSH. This article observed and compared the basic level of LH and FSH in two groups of patients with secondary amenorrhea, as well as the response to exogenous LH-RH injection in an attempt to elucidate the etiology of anovulation.