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总结两家医院自1969年12月~1995年4月手术治疗食管(贲门)恶性肿瘤7920例,共发现食管癌肉瘤18例,发生率为0.23%。资料表明,平均发病年龄54.7岁,男性多见,男女之比为2.6:1。临床症状主要为缓慢加重的吞咽困难,好发于食管中段,X线表现为食管腔内巨大充盈缺损。病变处食管梭形膨大,很少见到周围软组织块影。食管镜检查可见食管腔内息肉样肿物突出,活检报告多为鳞癌。病理特征为癌与肉瘤两种成分并存,无鳞状上皮癌与肉瘤之间的过渡形态。手术切除率高,极少转移,预后较好。
Summarizing the two hospitals from December 1969 to April 1995 surgical treatment of esophageal (cardia) cancer in 7920 cases, a total of 18 cases of esophageal carcinosarcoma were found, the incidence was 0.23%. The data show that the average age of onset is 54.7 years old, males are more common, and the ratio between males and females is 2.6:1. The main clinical symptoms were slowly increasing dysphagia, which occurred in the middle esophagus. X-ray showed a large filling defect in the esophageal cavity. Esophageal spindle enlargement of lesions, rarely seen around the soft tissue block. Esophagoscopy revealed prominent polypoid tumors in the lumen of the esophagus. Biopsy reports were mostly squamous cell carcinoma. The pathological feature is the presence of both cancerous and sarcoma components, with no transitional morphology between squamous cell carcinoma and sarcoma. Surgical resection rate is high, very few metastases, and the prognosis is better.