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目的了解某鞋厂流感暴发的疫情特征和病原体,为制定预防控制措施提供科学依据。方法按2005年广东省卫生厅《广东省流感样病例暴发疫情报告及调查处理工作指引(试行)》进行现场调查和处理。采用胶体金法、RT-PCR方法进行病原学检测。结果共发生217例流感样病例,罹患率为1.05%,其中以第二分厂发病罹患率最高(1.81%)。疫情持续25d,男女发病比例为1∶8,男性罹患率为0.43%,女性罹患率为1.27%,女性发病率高于男性并有统计学意义(χ2=26.8,P<0.01)。15.7%的病例集中在20岁组人群;二分厂生产车间的管理及其他人员发病较精致线上的人员高。实验室分离鉴定为H3亚型病毒。结论根据流行病学调查、临床表现和实验室检测,确定此起流感由H3亚型流感病毒引起。
Objective To understand the epidemic characteristics and pathogens of a flu outbreak in a shoe factory and provide a scientific basis for making prevention and control measures. Methods According to the Guangdong Provincial Department of Health “Outbreaks of Influenza-like Cases in Guangdong Province in 2005 and Guidelines for Investigation and Treatment (for Trial Implementation)” conducted on-site investigation and handling. Colloidal gold method, RT-PCR method for etiological testing. Results A total of 217 influenza-like cases were found, with an attack rate of 1.05%, of which the highest attack rate was found in the second branch (1.81%). The outbreak rate lasted for 25 days. The incidence of males and females was 1: 8. The incidence of males was 0.43% and the incidence of females was 1.27%. The incidence of females was higher than that of males (χ2 = 26.8, P <0.01). 15.7% of the cases were concentrated in the 20-year-old group; the management of the second branch workshop and other personnel were more sophisticated in line. Laboratory isolation and identification as H3 subtype virus. Conclusions Based on epidemiological investigations, clinical manifestations and laboratory tests, it was determined that the influenza was caused by the H3 subtype influenza virus.