钙通道阻滞剂(Calcium Channel Blockers),又称慢通道阻滞剂(Slow Channel Blockers)。是一类选择性阻断Ca~(2+)经细胞膜钙通道进入细胞内的药物。所以也有称Ca~(2+)内流阻滞剂(Calcium Entry Blockers),简称钙拮抗剂。自70年代后期以来,钙拮抗剂研究进展较快,尤其是二氢吡啶衍生物,许多新品种相继出现,临床应用十分广泛,特别是用在心血管方面。 Calcium Channel Blockers, also known as Slow Channel Blockers. Is a class of selective blocking Ca ~ (2+) through the cell membrane calcium channel into the drug. So also called Ca ~ (2) influx blockers (Calcium Entry Blockers), referred to as calcium antagonists. Since the late 1970s, research on calcium antagonists has progressed rapidly. Dihydropyridine derivatives, in particular, have emerged in many new varieties and have been widely used clinically, especially in the cardiovascular field.