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作者对里约热内卢市低收入人群中155名2月龄儿童接种脊髓灰质炎疫苗,其中80名接种脊髓灰质炎灭活疫苗(IPV);75名接种口服脊髓灰质炎疫苗(OPV)。免疫程序为:在接种脊髓灰质炎疫苗的同时也接种DTP,分别于2、4和6月龄接种3次,并在接种前及6月龄和最终9月龄接种麻疹疫苗时采集血标本。免疫使用的三价OPV和IPV均由法国Merieux研究所提供,每剂OPV含Ⅰ型病毒为100万TCD_(50)、Ⅱ型为10万TCD_(50)和Ⅲ型为30万TCD_(50)。每剂IPV含Ⅰ、Ⅱ和Ⅲ型病毒40-8-32D抗原单位。用微量中和试验
The authors vaccinated 155 2-month-old children in the low-income population of Rio de Janeiro against poliomyelitis vaccine, of whom 80 were vaccinated against poliomyelitis (IPV) and 75 were vaccinated against oral polio vaccine (OPV). The immunization schedule was as follows: DTP was inoculated simultaneously with the polio vaccine, three times at 2,4 and 6 months of age respectively, and blood samples were collected before and at the 6-month and 9-month-old measles vaccination. The trivalent OPV and IPV for immunization were provided by Merieux Institute of France. Each OPV contained 1000000 TCD_ (50) of type I virus, 100000 TCD_ (50) for type Ⅱ and 300000 TCD_ (50) for type Ⅲ. . Each dose of IPV contains Type I, Type II and Type III viruses 40-8-32D antigen units. Use trace neutralization test