论文部分内容阅读
构成心肌细胞动作电位的各种离子电流具有不同的特征。随着心肌电生理研究的进展和电压钳制技术的应用,现已基本阐明了各种离子电流的动力学特征。心肌细胞膜有快通道和慢通道,分别通过快内向电流和慢内向电流,形成心肌细胞复杂的动作电位。心肌细胞慢钙内向电流除了与动作电位去极、平台期、长不应期、较高自律性、心肌收缩力以及对神经体液调节和心肌代谢因素的依赖性等等有关外,尚在某些心律失常的发生中起重要作用。为此,本文就心肌细胞慢内向电流与心律失常的关系作一简要介
The various ion currents that make up the cardiomyocyte action potentials have different characteristics. With the progress of myocardial electrophysiology and the application of voltage clamping technology, the kinetic characteristics of various ion currents have been basically elucidated. Myocardial cell membrane fast channel and slow channel, respectively, through the rapid inward current and slow inward current, the formation of complex myocardial action potential. In addition to the cardiomyocyte calcium current inward current with the action potential to the extreme, plateau, refractory period, high self-discipline, myocardial contractility and neurohumoral regulation and myocardial metabolism and other factors, etc., is still some Arrhythmias play an important role. To this end, this paper on the slow cardiomyocyte inward current and arrhythmia a brief introduction