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目的探讨支气管哮喘合并抑郁症状对治疗依从性及临床疗效的影响。方法以2011年1月1日至2015年1月1日在呼吸内科住院治疗的支气管哮喘合并抑郁症状的190例患者为观察组,不伴抑郁症状的100例支气管哮喘患者为对照组。两组患者均予以相同的常规治疗,回顾性统计分析两组患者的治疗依从性、气促恢复时间、疗效和住院时间。结果观察组的治疗依从率为76.8%,显著低于对照组92.0%,差异有统计学意义(χ~2=10.23,P=0.00);观察组气促喘息的恢复时间和住院时间均显著长于正常组与,差异有统计学意义(分别P=0.00、0.02);观察组治疗总有效率70.0%显著低于对照组85.0%(χ~2=4.2,P=0.02)。结论支气管哮喘合并抑郁症状影响治疗依从性和疗效。
Objective To investigate the effect of bronchial asthma combined with depressive symptoms on treatment compliance and clinical efficacy. Methods A total of 190 patients with bronchial asthma with depression symptoms admitted to Department of Respiratory Medicine from January 1, 2011 to January 1, 2015 were enrolled as observation group and 100 patients without bronchial asthma as control group. The two groups of patients were treated with the same routine treatment, retrospective statistical analysis of two groups of patients compliance, shortness of breath recovery, efficacy and length of stay. Results The treatment compliance rate in the observation group was 76.8%, which was significantly lower than that in the control group (92.0%) (χ ~ 2 = 10.23, P = 0.00). The recovery time and hospital stay of the observation group were significantly longer than those of the control group The normal group and the difference was statistically significant (P = 0.00,0.02, respectively). The total effective rate in the observation group was 70.0%, which was significantly lower than that in the control group (85.0%, χ ~ 2 = 4.2, P = 0.02). Conclusion Bronchial asthma with depression symptoms affect the treatment compliance and efficacy.