目前国内外均广泛研究铂络合物的抗癌作用,继于顺氯氨铂(DDP)后第二代的铂类抗癌药—碳铂(Carboplatin),最近报道它具有疗效优于DDP,且肾毒性极少。另本实验室也发现Ⅵ价铂二羟基丙二酸二氨铂和二羟二氯二异丙胺铂有明显的抗癌活性,抗瘤谱广,肾毒性小,疗效不亚于DDP。同时体外研究发现二羟二氯二异丙胺铂(CHIP)的抗 At present, the anticancer effect of platinum complexes has been widely studied at home and abroad, followed by the second generation of platinum-based anticancer drug Carboplatin after DDP, and it has recently been reported that it has superior efficacy over DDP. And kidney toxicity is minimal. In addition, the laboratory also found that VI platinum dihydromalonic acid diammine platinum and dihydrochloride diisopropylamine platinum has obvious anti-cancer activity, broad spectrum anti-tumor, small renal toxicity, efficacy as much as DDP. At the same time, in vitro studies have found resistance to dichlorodichlorodiisopropylamine platinum (CHIP)