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目的探究腹腔镜下结直肠癌合并肝转移癌一期同时切除术的安全性及可行性。方法选取68例2012年11月~2015年6月至我院以及中山大学孙逸仙纪念医院胃肠外科二区就诊的结直肠癌合并肝转移癌患者,将所有患者分为两组,观察组34例,对照组34例。观察组采取腹腔镜下结直肠癌合并肝转移癌同期切除术,对照组采取传统的开腹结直肠癌合并肝转移癌同期切除术。记录两组患者术中出血量、手术时间、术后排气时间、总住院时间、术后并发症,对两组疗效、总生存期和无瘤生存期进行分析。结果观察组术中出血量、手术时间、术后排气时间、总住院时间与对照组相比,有统计学意义(P<0.05);虽然观察组的术并发症比对照组低,但两组术后并发症比较无统计学意义(P>0.05)。结论全腹腔镜下结直肠癌合并肝转移癌一期联合切除安全可行,总体临床效果优于开腹手术。
Objective To investigate the safety and feasibility of simultaneous laparoscopic resection of colorectal cancer with liver metastasis. Methods Sixty-eight patients with colorectal cancer complicated with liver metastasis who were admitted to our hospital from November 2012 to June 2015 in our hospital and Sun Yat-sen Memorial Hospital of Sun Yat-sen Memorial Hospital were enrolled. All the patients were divided into two groups. The observation group consisted of 34 cases , Control group 34 cases. The observation group was treated by laparoscopic resection of colorectal cancer with resection of liver metastases, while the control group was treated by conventional open resection of colorectal cancer with resection of liver metastases. The intraoperative blood loss, operation time, postoperative exhaust time, total length of stay and postoperative complications were recorded. The curative effect, overall survival and disease-free survival of the two groups were analyzed. Results The intraoperative blood loss, operation time, postoperative exhaust time and total hospital stay were statistically significant (P <0.05). Although the operative complications in the observation group were lower than those in the control group, The postoperative complications were not statistically significant (P> 0.05). Conclusions Total laparoscopic colorectal cancer with liver metastases combined with resection of a safe and feasible, the overall clinical effect is superior to open surgery.