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目的:评价卡前列素氨丁三醇与宫腔填纱联用治疗前置胎盘剖宫产产后出血患者的临床疗效。方法:选取2013年1月—2015年2月间收治的前置胎盘剖宫产患者82例,将其依据不同的治疗方法分为对照组与观察组,每组41例;对照组患者均给予缩宫素与宫腔填纱联用以预防产后出血,观察组患者在对照组治疗的基础上再给予卡前列素氨丁三醇注射液治疗,比较两组患者的临床疗效。结果:经治疗,观察组患者术后2 h和24 h出血量均显著少于对照组(P<0.05);两组患者治疗前后的血压、血氧饱和度及脉搏值经比较其差异无统计学意义(P>0.05)。结论:卡前列素氨丁三醇与宫腔填纱联用治疗前置胎盘剖宫产产后出血患者的临床疗效优于缩宫素的治疗,且安全性较好,对患者机体影响较小。
OBJECTIVE: To evaluate the clinical efficacy of carboprost trometamol in combination with uterine filling in the treatment of pre-placental cesarean section postpartum hemorrhage. Methods: From January 2013 to February 2015, 82 cases of placenta accreta in the placenta previa were selected and divided into control group and observation group according to different treatment methods, 41 cases in each group. Patients in the control group were given Oxytocin and uterine filling yarn combined to prevent postpartum hemorrhage, observation group patients in the control group based on the treatment given carboprost trometamol injection, the clinical efficacy of the two groups were compared. Results: After treatment, the bleeding volume of observation group was significantly less than that of control group at 2 h and 24 h after operation (P <0.05). There was no statistical difference in blood pressure, oxygen saturation and pulse rate between the two groups before and after treatment Significance (P> 0.05). CONCLUSION: The combination of carboprost trometamol and uterine filling in treating placenta previa patients with postpartum hemorrhage is superior to oxytocin in the treatment of postpartum hemorrhage, and has better safety and less impact on the patient’s body.