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目的： 探讨喉癌治疗方法的选择和分析喉癌治疗失败的原因。方法：总结本科 1989～ 1991年 3年间经根治的 151例喉癌病例，分单纯放疗、全喉切除术、部分喉切除术、挽救性手术 4个治疗组，分析各组的 3年和 5年生存率以及各组的失败原因。结果：单纯放疗组、全喉切除组、部分喉切除组、挽救性手术组的 3年和 5年生存率，分别为 45.9％ ,66.7％ ,94.4％ ,88.9％和 24.3％ ,56.5％ ,86.1％ ,66.7％，各组间差异有显著性；在晚期（Ⅲ＋Ⅳ期）病例中， 3年和 5年生存率分别为 27.3％ ,65.2％ ,87.5％ ,75.0％ 和 9.1％ ,54.5％ ,62.5％ ,50.0％，组间有显著性差异；在早期（Ⅰ＋Ⅱ期）病例中，单纯放疗组、部分喉切除组、挽救性手术组的 3年 和 5年生存率分别为 73.3％ ,96.4％ ,100.0％和 46.7％ ,92.6％ ,80.0％ ,各组间有显著性差异。各组治疗失败的原因均以原发灶复发为主。结论：喉癌的治疗以手术疗效最好；原发灶复发是喉癌治疗失败的主要原因。
Objective: To explore the choice of treatment of laryngeal cancer and analyze the causes of laryngeal cancer failure. Methods: To summarize the 151 cases of laryngeal cancer who underwent radical operation during the three years from 1989 to 1991, and divided into 4 groups: radiotherapy, total laryngectomy, partial laryngectomy and salvage surgery. The 3-year and 5-year Survival rate and the reasons for the failure of each group. Results: The 3-year and 5-year survival rates of radiotherapy group, total laryngectomy group, partial laryngectomy group and salvage operation group were 45.9%, 66.7%, 94.4%, 88.9% and 24.3%, 56.5% and 86.1 %, 66.7% respectively. The 3-year and 5-year survival rates were 27.3%, 65.2%, 87.5%, 75.0% and 9.1%, 54.5% and 62.5 %, 50.0% respectively. The 3-year and 5-year survival rates of the radiotherapy group, partial laryngectomy group and salvage operation group were 73.3% and 96.4% respectively in the early stage (stage Ⅰ + Ⅱ) 100.0% and 46.7%, 92.6% and 80.0%, respectively, with significant differences among the groups. The reasons for the failure of treatment in each group were mainly primary tumor recurrence. Conclusion: The treatment of laryngeal cancer is the best surgical treatment; recurrence of primary laryngeal cancer treatment is the main reason for the failure.