This paper is concerned with the linear quadratic regulation (LQR) problem for both linear discrete-time systems and linear continuous-time systems with multipl
动脉粥样硬化(Atherosclerosis,AS)是冠脉综合征的病理基础,严重危害人类健康。据统计约有15.4万人患有心脑血管疾病和动脉粥样硬化。在动脉粥样硬化发展过程中伴随炎症的侵袭,导致斑块处活化的巨噬细胞分泌大量的基质金属蛋白酶(matrix metalloproteinases,MMPs),后者可以降解细胞外基质增加心脑血管疾病的发病率和死亡率。基质金属蛋白酶-9(matrix meta