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观察谷胱甘肽滴眼剂进口与国产制剂治疗老年皮质性、核性白内障的临床安全性及有效性。临床试验采用随机对照,人选患者为50例,其中国产制剂组为30例、30只眼,进口制剂组20例、20只眼。治疗组使用国产的2%谷胱甘肽滴眼剂,剂量每次为1-2滴,每日三次;对照组使用进口2%谷胱甘肽滴眼剂,剂量每次为1-2滴,每日三次。两组治疗疗程均为半年。结果表明,按国际标准视力提高两行以上者,治疗组为56.6%,对照组为40.0%,经统计学处理,差异无显著性(P>0.05)。
To observe the clinical safety and efficacy of glutathione eye drops imported and domestic preparations in the treatment of senile cortical and nuclear cataract. Randomized clinical trials using 50 patients were selected patients, including 30 cases of domestic preparation group, 30 eyes, 20 cases of imported preparation group, 20 eyes. The treatment group using domestic 2% glutathione eye drops, the dose of 1-2 drops three times a day; the control group imported 2% glutathione eye drops at a dose of 1-2 drops Three times a day. Treatment of two groups were six months. The results showed that according to the international standard of visual acuity improved more than two lines, the treatment group was 56.6%, the control group was 40.0%, by statistical analysis, the difference was not significant (P> 0.05).