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0 引言 前列腺特异抗原 (prostate- specific antigen,PSA)是一种灵敏度较高的肿瘤标志物 [1 ] .抗 PSA/ CD3双特异单链抗体 (single chain antibody,Sc Fv) ,能同时识别 T细胞上的 CD3分子和前列腺癌的特异性抗原 PSA.我们在已构建抗 CD3Sc Fv和抗 PSA Sc Fv的基础上[2 ,3]
0 Introduction Prostate-specific antigen (PSA) is a highly sensitive tumor marker. [1] Anti-PSA / CD3 double-chain scfv (ScFv) On CD3 molecules and prostate cancer specific antigen PSA we have built anti-CD3Sc Fv and anti-PSA Sc Fv on the basis of [2, 3]