论文部分内容阅读
慢性粒细胞白血病(慢粒)终末期有急剧的变化过程,其表现形式有下述几种类型:(1)对各种药物耐药,白细胞总数增加,而造血组织没有明显的原始细胞增高,血小板降低,(2)进行性骨髓纤维化伴有贫血,血小板减少,白细胞总数增高,(3)不成熟白细胞增高,但病情进展缓慢,病程可超过6个月或1～2年,输血常有效(Spiers称为混合型),(4)原始细胞危象(Bla-stic cell Crisis)或急性变(Acute trans-formation),其中有一型称为暴发性原始细胞白血病(Fulminating blast cell leu-kemia)或暴发性变态(Fulminuting-metamorphosis),为极重型。具发病急骤,
Chronic myeloid leukemia (CML) has a sharp change in the end-stage, its manifestations are the following types: (1) resistant to various drugs, the total number of white blood cells increased, and hematopoietic tissue no significant increase in blasts, (2) progressive myelofibrosis associated with anemia, thrombocytopenia, increased total leukocytes, (3) an increase in immature leukocytes, but the disease progresses slowly and may last longer than 6 months or 1 to 2 years (Spiers called hybrid), (4) Bla-stic cell crisis or Acute trans-formation, of which a type is known as fulminating blast cell leukemia (Fulminating blast cell leukemia) Or fulminating-metamorphosis, is extremely heavy. With sudden onset,