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目的：研究右美托咪啶在ICU镇静作用的临床效果。方法选取我院自2014年2月-2016年2月ICU收治的80例患者作为观察对象，随机分为对照组与治疗组2组，对照组实施咪达唑仑治疗，治疗组则实施右美托咪啶治疗。对比2组患者的镇静效果情况。结果治疗组患者的镇静效率为82.50%，明显高于对照组患者的65.00%（P<0.05）；治疗组患者的NRS评分、静推芬太尼次数、Ramsay评分等各项指标均明显优于对照组患者（P<0.05）。结论给予ICU患者右美托咪啶治疗，镇痛及镇静效果明显，血流动力稳定，值得临床上推广及应用。“,”Objective:To study the clinical efficacy of dexmedetomidine sedation in the ICU.Methods:selected in our hospital from February 2014 to 2016 February admitted to the ICU of 80 patients as observation objects,were randomly divided to control group and treatment group 2 group,control group received midazolam treatment,the treatment group is implemented dexmedetomidine treatment.The sedative effects of the 2 groups were compared.Results:the treatment group patients sedation rate was 82.50%,significantly higher than that of the control group was 65.00%(P < 0.05);treatment group with NRS score,intravenous fentanyl times,Ramsay score and other indicators were significantly better than those of the control group(P < 0.05).Conclusion:given ICU patients with dexmedetomidine treatment,analgesic and sedative effect is obvious,hemodynamic stability,worthy of clinical popularization and application.