目的　研究急性胰腺炎的胃粘膜病变特点及与幽门螺杆菌 (HP)感染的关系。方法　慢性胃炎诊断标准参照最新悉尼分类系统 ,幽门螺杆菌检测采用快速尿素酶试验、病理组织学染色及 1 3C呼气试验。结果　急性胰腺炎患者胃粘膜病变发生率高 ,其幽门螺杆菌感染率与慢性胃炎患者无显著性差异。结论　急性胰腺炎可导致胃粘膜病变 ,幽门螺杆菌感染不是其直接原因 Objective To study the characteristics of gastric mucosal lesions in acute pancreatitis and its relationship with Helicobacter pylori (HP) infection. Methods Chronic gastritis diagnostic criteria with reference to the latest Sydney classification system, detection of Helicobacter pylori rapid urease test, histopathological staining and 1 3C breath test. Results The incidence of gastric mucosal lesions in patients with acute pancreatitis was high, and the rate of Helicobacter pylori infection was not significantly different from that of patients with chronic gastritis. Conclusions Acute pancreatitis can cause gastric mucosal lesions, and H. pylori infection is not the direct cause